With Major League Soccer unveiling the full 2021 season schedule, the Portland Timbers will be opening their campaign on the road on April 18 against their Cascadia foe the Vancouver Whitecaps FC at Rio Tinto Stadium in Sandy, Utah.
This news comes on the travel restrictions between the U.S. and Canada, the Whitecaps will host matches at Rio Tinto Stadium until a new announcement of a return to their home market in BC Place is permitted.
The television schedule for the Timbers this season will be with at least 10 games broadcast nationally, with 5 games on the road and five at home via ABC and ESPN. The highlight of those games is the always contested Cascadia Derby as all three matches against the Seattle Sounders will be nationally televised.
On the local scene 16 games will be televised by FOX 12 and the other eight on ROOT Sports.
The Portland Timbers will face just two Eastern conference opponents this season, traveling to Philadelphia on May 30 and then on October 3 to play Inter Miami for the first time in team history.
In addition to first-time meetings, the Rose City side will square off against conference rival and expansion side Austin FC twice on the road at Q2 Stadium on July 3 and August 21 and Decision Day at Providence Park on November 7.
Still, the Portland Timbers will have to play host to Club C.D. Marathon in a round of 16 of the Scotiabank Concacaf Champions League matches, traveling to San Pedro Sula on April 6 and returning to Providence Park on April 13.
Source: Portland Timbers Communications
| Date | Opponent | Kickoff | Television |
| Sunday, April 18 | @Vancouver Whitecaps FC | 7 p.m. | ROOT SPORTS |
| Saturday, April 24 | HOUSTON DYNAMO FC | 7:30 p.m. | FOX 12 PLUS |
| Saturday, May 1 | @FC Dallas | 5 p.m. | FOX 12 PLUS |
| Sunday, May 9 | SEATTLE SOUNDERS FC | 12 noon | ABC |
| Saturday, May 15 | @San Jose Earthquakes | 7 p.m. | FOX 12 PLUS |
| Saturday, May 22 | LA GALAXY | 12:30 p.m. | ABC |
| Sunday, May 30 | @Philadelphia Union | 2:30 p.m. | FS1 |
| Saturday, June 19 | SPORTING KANSAS CITY | 7:30 p.m. | FOX 12 PLUS |
| Wednesday, June 23 | @Houston Dynamo FC | 5:30 p.m. | ROOT SPORTS |
| Saturday, June 26 | MINNESOTA UNITED FC | 7:30 p.m. | ROOT SPORTS |
| Saturday, July 3 | @Austin FC | 6 p.m. | FOX 12 PLUS |
| Saturday, July 17 | FC DALLAS | 7:30 p.m. | FOX 12 PLUS |
| Wednesday, July 21 | LOS ANGELES FC | 7:30 p.m. | ROOT SPORTS |
| Saturday, July 24 | @Minnesota United FC | 5 p.m. | FOX 12 PLUS |
| Friday, July 30 | @LA Galaxy | 7 p.m. | ESPN |
| Wednesday, Aug. 4 | SAN JOSE EARTHQUAKES | 7:30 p.m. | ROOT SPORTS |
| Saturday, Aug. 7 | REAL SALT LAKE | 7:30 p.m. | ROOT SPORTS |
| Sunday, Aug. 15 | SEATTLE SOUNDERS FC | 5:30 p.m. | FS1 |
| Wednesday, Aug. 18 | @Sporting Kansas City | 5:30 p.m. | FOX 12 PLUS |
| Saturday, Aug. 21 | @Austin FC | 6 p.m. | FOX 12 PLUS |
| Sunday, Aug. 29 | @Seattle Sounders FC | 7:30 p.m. | ESPN |
| Friday, Sept. 3 | @Houston Dynamo FC | 5 p.m. | UniMas |
| Friday, Sept. 10 | @Vancouver Whitecaps FC | TBD | FOX 12 PLUS |
| Wednesday, Sept. 15 | COLORADO RAPIDS | 7 p.m. | ROOT SPORTS |
| Sunday, Sept. 19 | LOS ANGELES FC | 3 p.m. | FS1 |
| Saturday, Sept. 25 | REAL SALT LAKE | 7:30 p.m. | FOX 12 PLUS |
| Wednesday, Sept. 29 | @Los Angeles FC | 7 p.m. | FS1 |
| Sunday, Oct. 3 | INTER MIAMI CF | TBD | FS1 |
| Saturday, Oct. 16 | @LA Galaxy | 7:30 p.m. | FOX 12 PLUS |
| Wednesday, Oct. 20 | VANCOUVER WHITECAPS FC | 7 p.m. | FOX 12 PLUS |
| Saturday, Oct. 23 | @Colorado Rapids | 6 p.m. | FOX 12 PLUS |
| Wednesday, Oct. 27 | SAN JOSE EARTHQUAKES | 7 p.m. | FOX 12 PLUS |
| Wednesday, Nov. 3 | @Real Salt Lake | 6:30 p.m. | ROOT SPORTS |
| Sunday, Nov. 7 | AUSTIN FC | 3 p.m. | FOX 12 PLUS |
